On behalf of the Spanish Society of Immunology (SEI) and the University of Alicante (UA), the International Trained Immunity (INTRIM) consortium, and the Marie Skłodowska-Curie Innovative Training Network INsTRuCT, we welcome you to the second international Alicante-Winter Immunology Symposium in Health (A-WISH), which is taking place on December 15th-16th 2022 in the city of Alicante, Spain.